I Am Legend. Dog is infected by a zombie-esque virus and is killed by her owner.

Subsequently, question is, did Will Smith keep the dog from I Am Legend? During the filming of I Am Legend, Will Smith got so attached to his co-star (Abbey the dog), that he begged the trainer to let him keep her. The trainer refused, but offered to bring Abbey to Smiths house every weekend.

Considering this, does Sam die in I Am Legend?

Samantha, also known as Sam, was the deuteragonist of I Am Legend. She was Robert Nevilles beloved German Shepherd companion and best friend, and a survivor of the Krippin Virus.

Samantha Appearance I Am Legend (film) Status Deceased (Smothered by Robert Neville after succumbing to the Krippin Virus)
What happens in the end of I Am Legend?

The ending to the Alternate Theatrical Version varies from the original ending. Instead of blowing himself and the hemocytes up with a grenade, Neville discovers that the hemocytes actually came for the female he captured earlier in the movie. He relieves her of the cure and returns her to the hemocytes.