What drug is given as an antidote to warfarin?

[happyduck881]

Withholding 1 or more doses of warfarin is usually sufficient if INR is excessively elevated or if minor bleeding occurs. If overdose occurs or anticoagulation needs to be immediately reversed, the antidote is vitamin K (phytonadione, Aquamephyton).

[angrypanda814]

Warfarin (a blood-thinning drug) is used to treat blood clotting disorders. The blood-thinning action of warfarin is gauged by a blood test called the INR. Current guidelines advocate the administration of a fixed-dose of vitamin K, the antidote to warfarin, as a way of reversing high INR values.

Secondly, which is the antidote for heparin? protamine sulfate

Keeping this in view, how do you reverse warfarin overdose?

Another therapeutic approach would be to withhold 1 dose of warfarin and orally administer vitamin K1, 1-2.5 mg, particularly if the patient is at increased risk of bleeding. For more rapid reversal (eg, urgent surgery), administer vitamin K1, 2.5-5 mg, orally (expected reduction of the INR should occur in about 24 h).

What is a dangerous INR level?

If an INR score is too low, a patient can be at risk for a blood clot. However, if the INR is too high, patients could also experience bleeding. A typical INR score ranges between 2 to 3. The “ideal” INR score can vary from patient to patient.