I live here and I would like to comment on some things that might be different from what you expect: - Walkability: Definitely not great the city is huge, there are neighborhood where is safe to walk, with interesting stuff to do, but this isn't the case on most places far from west zone (Pinheiros and Vila Madalena) and Paulista avenue. Expect to use public transportation (subway and buses) and uber a lot. - LGBTQ+: Sao Paulo is the state with most homicides against trans people in the whole country. Violence against all LGBTQ+ is surging rampantly, you can search for it, there are some good of articles in English with data. - Hospitals: There are great hospitals here, but they are, as a majority, private and will cost you to use any service. Public hospitals are available, but don't expect English speaking staff or short queues, they are pretty packed (even after midnight). Prices are way off too, in the good and safe neighborhoods, don't expect to pay less that 10USD for a meal in a sit-in restaurant. There are cheaper options, but they will hardly have English speaking staff.